Impurity-6

CAS No: 253870-02-9
Chemical Name:
5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Molecular Formula:
C8H9NO3

Impurity-5

CAS No: NA
Chemical Name:
5,5'-difluoro-3-hydroxy-3,3'-biindoline-2,2'-dione
Molecular Formula:
C16H10F2N2O3

Sunitinib NN-dimethyl impurity

CAS No: 326914-17-4
Chemical Name:
(Z)-N-(2-(dimethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C20H23FN4O2

5-Fluoroisatin

CAS No: 443-69-6
Chemical Name:
5-fluoroindoline-2,3-dione
Molecular Formula:
C8H4FNO2

USP Alcohol impurity

CAS No: 2377533-90-7
Chemical Name:
(Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2-(hydroxymethyl)-4-methyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C22H27FN4O3

Impurity-4

CAS No: 351-09-7
Chemical Name:
(E)-N-(4-fluorophenyl)-2-(hydroxyimino)acetamide
Molecular Formula:
C8H7FN2O2

Impurity-3

CAS No: 2199-59-9
Chemical Name:
ethyl 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylate
Molecular Formula:
C10H13NO3

USP E-Isomer

CAS No: 1691223-83-2
Chemical Name:
(E)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C22H27FN4O2

USP Aldehyde impurity

CAS No: 2377533-92-9
Chemical Name:
(Z)-N-(2-(diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2-formyl-4-methyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C22H25FN4O3

Ethyl amide impurity

CAS No: 1467015-10-6
Chemical Name:
(Z)-N-ethyl-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C18H18FN3O2

Acid impurity

CAS No: 452105-33-8
Chemical Name:
(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid
Molecular Formula:
C16H13FN2O3

Amide impurity

CAS No: 1186651-51-3
Chemical Name:
(Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C16H14FN3O2

N-Oxide impurity

CAS No: 356068-99-0
Chemical Name:
(Z)-N,N-diethyl-2-(5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamido)ethanamine oxide
Molecular Formula:
C22H27FN4O3

N-3-(Dimethylamino)propyl Impurity

CAS No: 2417674-06-5
Chemical Name:
(Z)-N-(3-(dimethylamino)propyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C21H25FN4O2

Reference standared

CAS No: 557795-19-4free base 11585 60-63-4(malate salt)
Chemical Name:
(Z)-Sunitinib; N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide;
Molecular Formula:
C22H27FN4O2

N-Desethyl Sunitinib

CAS No: 356068-97-8
Chemical Name:
(Z)-N-(2-(ethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C20H23FN4O2

Impurity-2

CAS No: 56341-41-4
Chemical Name:
5-fluoroindolin-2-one
Molecular Formula:
C8H6FNO

Impurity-1

CAS No: 356068-86-5
Chemical Name:
N-(2-(diethylamino)ethyl)-5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxamide
Molecular Formula:
C14H23N3O2